A sustained-release formulation of doxycycline hyclate (Atridox) prevents simultaneous infection of Anaplasma phagocytophilum and Borrelia burgdorferi transmitted by tick bite
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منابع مشابه
Sustained-release formulation of doxycycline hyclate for prophylaxis of tick bite infection in a murine model of Lyme borreliosis.
The prophylactic potential of a single injection of sustained-release doxycycline hyclate (Atridox) was compared to that of a single oral dose of doxycycline hyclate in a murine model of Lyme borreliosis. Prophylaxis, as measured by the lack of cultivable spirochetes and demonstrable pathology, was noted for 43% of orally treated mice; in contrast, the sustained-release doxycycline hyclate comp...
متن کاملBorrelia burgdorferi and Anaplasma phagocytophilum Coinfection
milder than the 1996 outbreak, with less illness and death; most patients had uncomplicated dengue fever, and only a few had DHF/DSS. Of the 874 serum samples that we tested, 456 (52.3%) were positive for denguespecific immunoglobulin M antibodies by enzyme-linked immunosorbent assay (Panbio, Sinnamon Park, Queensland, Australia), and more than one third of these were from patients in the 21to ...
متن کامل[Monoinfections caused by Borrelia burgdorferi and Borrelia burgdorferi / Anaplasma phagocytophilum co-infections in forestry workers and farmers].
BACKGROUND The presence of co-infections induced by tick-borne pathogens in humans is an important epidemiological phenomenon. This issue has attracted growing attention of doctors and people working under conditions of an increased risk of being exposed to tick bites. MATERIAL AND METHODS The research group consisted of 93 individuals with current anti-immunoglobulin M/G (IgM/ IgG) Borrelia ...
متن کاملTick-Borne Fever (Anaplasma phagocytophilum Infection) in Sheep – A Review
Ticks may transmit pathogens to ruminants worldwide, creating diseases such as anaplasmosis, babesiosis, ehrlichiosis and theileriosis. In Europe, the most important tick vector is Ixodes ricinus and the most widespread tick-borne infection in animals is Anaplasma phagocytophilum. This infection causes tick-borne fever (TBF) in ruminants, a disease which may not only cause suboptimal growth, bu...
متن کاملAssociation between the use of the acaricides, household type, tick bite and seropositivity against Anaplasma phagocytophilum and Borrelia burgdorferi sensu lato in clinically healthy dogs in Latvia
The aim of this study was to evaluate the association between seropositivity to Anaplasma phagocytophilum and Borrelia burgdorferi sensu lato and the following factors: (i) type of household (rural vs. urban), (ii) use of acaricides (type and seasonality/duration), and (iii) history of tick bite (season). Blood samples were collected from all the dogs in the household and dog owners were survey...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 2008
ISSN: 0022-2615,1473-5644
DOI: 10.1099/jmm.0.47535-0